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I have a Prairie system, but want to run ScanImage to take advantage of its features, e.g. bidirectional scanning. Is this possible? 

Yes. The ScanImage developers have not done this directly, but this has been successfully achieved within the the user community.

See PrairieScanImage.pdf for notes detailing how to accomplish this adaptation, under ScanImage 3.8. These notes were kindly provided by Chris Deister at Brown University. We have reviewed the notes for general accuracy, but again have not specifically tested this ourselves.

Additionally, Nathan Wilson et al have published a recent Nature Protocol that also includes a description of running ScanImage on a Prairie system.

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